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RNAProtein Synthesis SE
University: Harvard University
Course: Molecular Biology (BP 723)
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Student Exploration: RNA and Protein Synthesis
Vocabulary: amino acid, anticodon, codon, gene, messenger RNA, nucleotide,
ribosome, RNA, RNA polymerase, transcription, transfer RNA, translation
Prior Knowledge Questions (Do these BEFORE using the Gizmo.)
•Suppose you want to design and build a house. How would you communicate your
design plans with the construction crew that would work on the house?
Create a blueprint for the house.
•Cells build large, complicated molecules, such as proteins. What do you think cells
use as their “design plans” for proteins?
DNA
Gizmo Warm-up
Just as a construction crew uses blueprints to build a
house, a cell uses DNA as plans for building proteins. In
addition to DNA, another nucleic acid, called RNA, is
involved in making proteins. In the RNA and Protein
Synthesis Gizmo, you will use both DNA and RNA to
construct a protein out of amino acids.
•DNA is composed of the bases adenine (A), cytosine
(C), guanine (G), and thymine (T). RNA is composed
of adenine, cytosine, guanine, and uracil (U).
Look at the SIMULATION pane. Is the displayed
segment a part of a DNA or RNA molecule? How do
you know?
DNA because it has the base A-T and G-C
•RNA polymerase is a type of enzyme. Enzymes help chemical reactions occur
quickly. Click the Release enzyme button, and describe what happens.
The enzyme moves down the DNA molecule, separating the nucleotides.
Activity A:
Transcription
Get the Gizmo ready:
•If necessary, click Release enzyme.
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